ea0029p1552 | Steroid metabolism + action | ICEECE2012
Marine D.
, Bueno P.
, Silva R.
, Selistre-Araujo H.
, Nonaka K.
, Leal A.
Myostatin (MSTN) is a negative regulator of skeletal muscle growth, while androgens are strong positive regulators of muscle growth and strength. Follistatin (FS) is a binding protein which inhibits MSTN action. Evidences suggest that MSTN and testosterone actions in muscle may be associated. However, the mechanisms of androgens actions are not fully elucidated. The objective of this study was to evaluate the influence of exercise training in the expression of MSTN and FS in o...